23andMe Launches New Genetic Reports on Common Forms of Cancer

23andMe customers can now gain deeper insight into their likelihood of developing breast, colorectal, and prostate cancer through new reports based on polygenic risk scores (PRS) developed by 23andMe

SOUTH SAN FRANCISCO, Calif., March 06, 2024 (GLOBE NEWSWIRE) -- 23andMe Holding Co. (Nasdaq: ME), a leading human genetics and biopharmaceutical company, released three new genetic reports for 23andMe+ members on breast, colorectal and prostate cancer. The reports are based on statistical models known as polygenic risk scores (PRS), developed by 23andMe through its proprietary research database. These PRS reports calculate the likelihood of an individual developing one of these cancers, based on thousands of genetic variants associated with the disease.

Recent studies show a rise in younger people being diagnosed with cancer. A BMJ Oncology study revealed that between 1990 and 2019 cancer rates worldwide have risen 79% in people under the age of 50. A 2023 American Cancer Society report found that 20 percent of colorectal cancer diagnoses in 2019 were in patients under age 55, almost twice the rate in 1995. Breast and colorectal cancers were among the top three cancers with the highest numbers of early-onset diagnoses in 2019.

“Using these reports to understand your likelihood to develop common cancers is an important step toward further integrating genetics into healthcare,” said Noura Abul-Husn, Vice President of Genomic Health at 23andMe. “Today, there is increasing evidence and support for the use of PRS in personalized disease prevention, and certain medical specialties — including oncology — have already begun to adopt this to inform clinical decision-making. These new reports will help customers better understand their overall likelihood for developing these diseases, and enable them to work with their healthcare providers to implement prevention plans.”

The new reports released today were developed by 23andMe scientists and clinical experts, using the Company’s massive database of genetic and health information contributed by consented research participants. 23andMe now offers over 40 PRS reports, which utilize machine learning to analyze the complex interplay of thousands of genetic variants linked to specific conditions or diseases.

23andMe’s New Breast Cancer, Prostate Cancer, and Colorectal Cancer PRS Reports
The new 23andMe PRS reports focus on some of the most common cancers for which genetics are often a factor, noting where some customers may have an increased likelihood of developing these conditions relative to average. This is important because averages can mask large differences – some people have a higher chance of developing cancer and some a slightly lower chance, due to genetics and other factors. Importantly, healthy lifestyle habits can offset an increased genetic likelihood for developing these diseases, while routine screening can help with early detection.