Genenta to Provide Update on Lead Product Temferon
Prof. Luigi Naldini will present updates on the efficacy of Temferon in pre-clinical solid tumor models and preliminary clinical biological data confirming in patients
MILAN, Italy and NEW YORK, May 16, 2023 (GLOBE NEWSWIRE) -- Luigi Naldini, Ph.D., M.D., co-founder and Executive Scientific Board Chairman of Genenta Science S.p.A. (NASDAQ: GNTA),
a clinical-stage immuno-oncology company, will be presenting the company cell-based platform harnessing the power of hematopoietic stem cells to provide durable, safe, and well tolerated treatment
for solid tumors at several upcoming scientific congresses. Prof. Luigi Naldini will provide updates on the efficacy of Genenta's lead product candidate,
Temferon, in pre-clinical solid tumor models and preliminary clinical biological data confirming in patients at these congresses.
Genenta has a deep pipeline of potential candidates and therapeutic combinations at different stages of development. The drug at the most advanced stage of development is called Temferon, and is currently in clinical trials of humans - Phase 1/2a. Temferon uses the patient's own stem cells modified with Genenta's platform to express interferon alpha in the tumor - a well-known immunomodulatory protein that has been used in the clinic for decades for the treatment of a variety of cancers, but with limited current use because of the systemic tolerability. Genenta's platform makes it possible to precisely avoid exposing the whole body to not tolerable concentrations and to selectively bring therapeutic activity into the tumor. From pre-clinical experiments, it has been observed that Temferon allows the immune system to see the tumor and mount an effective immune response. Food and Drug Administration (FDA) has granted Orphan Drug Designation (ODD) to Temferon for the treatment of glioblastoma multiforme (GBM). Updated data will be provided during the following congresses.
ASTCT + EBMT Joint Basic and Translational Scientific Meeting
Type: keynote presentation
Date: May 24, 2023
6th Annual Symposium on Macrophage
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Type: live keynote presentation
Date: June 1, 2023
EACR 2023 Congress, the Annual Congress of the European Association for Cancer Research
Type: live keynote presentation
Date: June 14, 2023
In addition, Tim Obara, Business Development Consultant and Richard Slansky, Chief Financial Officer, will attend BIO International Convention in Boston, MA on June 5-8, 2023.
About Prof. Luigi Naldini, Ph.D., M.D., co-founder and Executive Scientific Board Chairman of Genenta.
For the past 25 years, he has pioneered the development and the applications of lentiviral vectors for gene therapy, which have become one of the most widely used tools in biomedical research and,
upon recently entering clinical testing, are providing a long-sought hope for cures for several currently untreatable and otherwise deadly human diseases. He has published over 280
scientific papers. He has a SCOPUS Author h-index of 101. Prof. Luigi Naldini has won numerous awards, including the Outstanding Achievement Award from
the American Society of Gene and Cell Therapy (ASGCT) in 2014, President of ESGCT in 2015, the Beutler Prize from the American Society of Hematology (ASH) in 2017 and the
Jeantet-Collen Prize for Translational Medicine in 2019.