Outcomes From Two New Head-to-Head Randomized Controlled Trials Involving the UroLift System Highlight a Superior Patient Experience* Against Rezūm and Its Advantage Over Medical Therapy as an Early Intervention for BPH

WAYNE, Pa., May 07, 2024 (GLOBE NEWSWIRE) -- Teleflex Incorporated (NYSE: TFX), a global leader in medical technologies, today announced the presentation of new research findings from the 2024 American Urological Association Annual Meeting in San Antonio, TX, May 3 – 6, 2024, showcasing excellent patient experience* with the Prostatic Urethral Lift (PUL) with the UroLift System for benign prostatic hyperplasia (BPH).

This year’s research marks the first time results from two randomized head-to-head trials were presented that reinforce the UroLift System as the leading minimally invasive surgical therapy (MIST) that can provide rapid relief and durable outcomes with preservation of sexual function.**^1-5

“These significant new randomized head-to-head studies and real-world analyses demonstrate the UroLift System provides distinctive patient experience* advantages, positioning it as an early treatment option compared to medications for men whose quality of life is impacted by oppressive BPH symptoms,” said Jacqueline Welch, Vice President of Global Clinical and Scientific Operations at Teleflex. “For over 10 years, Teleflex has advanced BPH research through numerous trials involving the UroLift system and now other contemporary treatments. Our continued investment and focus on direct comparative research helps to facilitate more informed discussions between clinicians and their patients about treatment options.”

The following research presentations outlined the key findings from the studies:

In the largest head-to-head randomized controlled trial (RCT) study (IMPACT), early patient outcomes were studied among UroLift PUL and Tamsulosin medication subjects.¹

• Preliminary data suggest that PUL with the UroLift system offers better symptom relief, quality of life improvements and patient satisfaction compared with alpha blockers within three months following the initiation of treatment.¹
  
• These findings could help to advance evidence-based shared decision making.¹

First head-to-head RCT study comparing UroLift System experience against Rezūm (CLEAR) showcases a superior early patient experience* with the UroLift System (PUL) compared with water vapor thermal therapy (WVTT).²

• Patients undergoing PUL with the UroLift System experienced more rapid symptom relief and quality of life improvements within the first three months post-treatment.²
  
• Outcomes can aid healthcare providers and patients in gaining a clearer understanding of the perioperative experience, facilitating informed decisions regarding treatment options.²

A comprehensive analysis of post-surgery medication usage over five years among patients treated with the UroLift System, transurethral resection of the prostate (TURP), and GreenLight photoselective vaporization of the prostate (PVP).³