Apellis Announces 11 Oral Presentations at the Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting - Seite 2

AI-based qOCT analysis of phase 3 trials OAKS & DERBY data on the effect of pegcetacoplan on geographic atrophy – Pallavi Bagga, Ph.D. – Tuesday, May 7 – 2:15‑2:30 PM PDT

Predictive value of the photoreceptor/RPE loss ratio on OCT in the management of geographic atrophy (GA) for patient selection and monitoring of therapeutic efficacy – Ursula Schmidt‑Erfurth, M.D. – Tuesday, May 7 – 2:30‑2:45 PM PDT

Rate of response to treatment in eyes with geographic atrophy treated with Pegcetacoplan in a within-patient comparison using automated AI-based OCT biomarker quantifications in OAKS, DERBY and GALE – Gregor S. Reiter, M.D., Ph.D. – Thursday, May 9 – 2:30‑2:45 PM PDT

IRIS Registry analysis of anti-VEGF treatment in patients with coexisting neovascular age-related macular degeneration and geographic atrophy – Theodore Leng, M.D., FACS – Thursday, May 9 – 3:15‑3:30 PM PDT

Poster presentations:

• Prevalence of outer retinal tubulation (ORT) and association with geographic atrophy (GA) growth among patients in the OAKS and DERBY trials – Kensington Hatcher, O.D., FAAO – Monday, May 6 – 3:00‑4:45 PM PDT
  
• Loss of independence in geographic atrophy (GA) - results from the MOSAIC study among patients and caregivers in Europe – Beverly Lui, PharmD – Thursday, May 9 – 8:00‑9:45 AM PDT
  
• Deep learning-based segmentation of geographic atrophy in fundus autofluorescence: external validation in imaging acquired in a clinical trial – Souvick Mukherjee, Ph.D. – Thursday, May 9 – 8:00‑9:45 AM PDT
  

About SYFOVRE (pegcetacoplan injection)
SYFOVRE (pegcetacoplan injection) is the first-ever approved therapy for geographic atrophy (GA). By targeting C3, SYFOVRE is designed to provide comprehensive control of the complement cascade, part of the body’s immune system. SYFOVRE is approved in the United States for the treatment of GA secondary to age-related macular degeneration.

About Geographic Atrophy (GA)
Geographic atrophy (GA) is an advanced form of age-related macular degeneration and a leading cause of blindness worldwide, impacting more than one million Americans and five million people worldwide.^1,2 It is a progressive and irreversible disease caused by the growth of lesions, which destroy the retinal cells responsible for vision. The vision loss caused by GA severely impairs independence and quality of life by making it difficult to participate in daily activities. On average, it takes only 2.5 years for GA lesions to start impacting the fovea, which is responsible for central vision.³